Citrus Aurantium Fruit Extract
Tangeretin is an O-polymethoxylated flavone that is found in tangerine and other citrus peels. Tangeretin strengthens the cell wall and acts as a plant's defensive mechanism against disease-causing pathogens.
It has also been used as a marker compound to detect contamination in citrus juices.
Although few randomized, double-blind human studies have been done, animal research shows the potential of tangeretin as a cholesterol lowering agent. A study on rats demonstrated potential protective effects against Parkinson's disease.
Tangeretin also shows enormous potential as an anti cancer agent. In in vitro studies, tangeretin appears to counteract some of the adaptations of cancer cells. Tangeretin induced apoptosis in leukemia cells while sparing normal cells. In a study on two human breast cancer cell lines and one colon cancer cell line, tangeretin blocked cell cycle progression at the G1 (growth) phase in all three cell lines, without inducing apoptosis in the tumor cell lines. Once tangeretin was removed from the tumor cells, their cell cycle progression returned to normal. Tangeretin also counteracts tumor suppression of gap junction intercellular signaling. In summary, in vitro studies show antimutagenic, antiinvasive and antiproliferative effects. One caveat is that tangeretin appears to counteract the anticancer drug tamoxifen and to suppress the activity of natural killer cells.
Tangeretin is commercially available as a dietary supplement.
Our Citrus Aurantium Fruit Extract holds minimum 98% tangeretin purity through an unique extraction and purification technology.
1kg, 2kg, 5kg/Drum or carton with aluminum foil bags inside or small package as customer's requirement; 10kg, 15kg, 25kg/Drum with double layers food grade plastic bag inside, external use cardboard drums.
CAS No.: 481-53-8
Molecular formula: C20H20O7
Molecular weight: 372.336900
Exact quality: 372.12100
Density: 1.277 g/mL at 25 °C (lit.) Boiling point: 157 °C 0.17 mm Hg(lit.) Flash point: >230 °F Refractive index: n20/D 1.551 (lit.) Water solubility: insoluble Steam pressure: 8.41E-13mmHg at 25°C
Dangerous goods transport code: UN 2811
Hazard Category Code: R25
Safety instructions: S45
RTECS number: DJ3102725
Dangerous goods mark: T
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Product Categories : Pharmaceutical Raw Materials(APIS)